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Hong Ji

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Review Open access Jul 2026

JAK/STAT signaling pathway inhibitors in neurodegenerative diseases: current status and future perspectives

This review systematically elucidates the core mechanisms of the JAK/STAT pathway in NDDs, including the regulation of microglial and astrocytic reactivity, the impact on blood–brain barrier integrity, and involvement in energy metabolism abnormalities.

Hai-Xia Yang, Bowei Su, Ya-Nan Bao et al. · 0 citations