Associations of SLCO gene polymorphisms with perampanel response and plasma concentrations in patients: a longitudinal retrospective real-world study in refractory epilepsy.
OBJECTIVE This study analyzed the correlation between SLCO gene polymorphisms and the efficacy and plasma concentrations of perampanel (PER) in pediatric patients with refractory epilepsy (RE). METHODS SLCO genotypes were detected using first-generation Sanger sequencing, and the plasma concentration of PER was measu...