Mailuoning oral liquid alleviates permanent ischemic stroke by targeting CCR5 to modulate microglial polarization and PI3K/AKT/mTOR axis.
BACKGROUND Ischemic stroke (IS) triggers neuroinflammation cascades where microglial polarization is a pathological determinant. Mailuoning oral liquid (MLN O) is clinically utilized to prevent thrombosis and treat convalescent IS, but its pharmacological targets in permanent IS remain unclear. AIM OF THE STUDY This...