Extensively Drug-Resistant ST16 Klebsiella pneumoniae Co-Harboring blaKPC-2, blaOXA-181, and Chromosomal blaNDM-4: Genomic Features and Therapeutic Challenges
Purpose Carbapenem-resistant Klebsiella pneumoniae (CRKP) represents a major global public health threat due to its high-level antimicrobial resistance and limited therapeutic options. The emergence of CRKP isolates co-harboring multiple carbapenemase genes further complicates clinical management and infection control....