Hong-Wei Zhou

Genetic and microbial regulation of NOD2 signaling in homeostasis and disease.

Lactobacillus johnsonii attenuates chronic stress-induced ovarian dysfunction by modulating ovarian clock-related steroidogenic signaling.

Chronic psychological stress is increasingly implicated in female reproductive disorders, yet the mechanistic link between stress and ovarian dysfunction remains incompletely understood. Using a chronic restraint stress (CRS) mouse model, we demonstrated that CRS induced anxiety-like behaviors and ovarian dysfunction,...

Artificial intelligence in laboratory medicine: From machine learning to large language models.

It is concluded that AI is best positioned, in the near term, as an assistive layer rather than an autonomous agent, and the rationale for developing vertically oriented, laboratory-specific foundation models that can integrate structured results, longitudinal patient data, quality-control metadata, instrument informat...