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Author

Hong-Yan Lin

2 papers indexed here

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Open access Aug 2026

A computational framework integrating a protein language model with alchemical simulation for gain-of-function enzyme design.

The ESM-FEP framework establishes a generalizable and efficient strategy for the rational design of gain-of-function enzymes, with broad applications in biocatalysis, bioremediation, and precision agriculture.

Long-Can Mei, Jian Wu, Li-Jun Chen et al. · 0 citations
Open access Aug 2026

Molecular basis of Arabidopsis ABCC2 in plant detoxification

Cryo-electron microscopy structures of At ABCC2 provide new insights into the detoxi cation mechanism of At ABCC2 and highlight the potential for using ABCC transporters to develop herbicide-resistant crops.

Jiang-Qing Dong, Tai-Li Yang, Xin-He Yu et al. · 0 citations

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