Piper nigrum L. and its main component piperine ameliorate hyperuricemia and hyperuricemia-related renal inflammation through suppressing the JAK2-STAT3-XDH/SOCS3/TNF-α signalling pathway
Hyperuricemia is a metabolic disease characterized by serum uric acid (UA) levels remaining above normal levels for a long period of time, which has become a huge challenge faced by society. The fruits of P. nigrum L. (P. nigrum) as traditional Indian medicine was used to treat various diseases. However, the anti-h...