Oct 2026
GRP75-dependent SIMPA mediates inter-organellar quality control.
Fan Yu, Ling-Yu Jiang, Han-Yu Liu et al.
· Nature · 0 citations
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Open access
Sep 2026
Targeting heparanase-associated epithelial glycocalyx remodeling attenuates Akt/NF-κB–related barrier dysfunction in experimental COPD
Background Chronic obstructive pulmonary disease (COPD) is characterized by persistent airway inflammation, epithelial barrier dysfunction, and progressive structural remodeling. Although glycocalyx impairment has been implicated in COPD pathogenesis, the mechanisms linking glycocalyx degradation to epithelial barrier...
Yue-Ping Bai, Xu-Shan Ma, Hong-Zhen Jin et al.
· Frontiers in Pharmacology · 0 citations