Open access
Sep 2026
DEFB1 + Cancer Cell-IFI30+ Macrophage Crosstalk Drives Immunosuppressive Niche in Intrahepatic Cholangiocarcinoma.
Intrahepatic cholangiocarcinoma (ICC) is a rare but highly aggressive primary liver malignancy distinguished by a profoundly heterogeneous tumor microenvironment, which underlies its limited response to targeted and immune-based therapies. Deciphering the cellular composition and intercellular signaling within this com...
Guo-Liang Wang, Hang Meng, Meng Li et al.
· Genomics, Proteomics & Bioin... · 0 citations