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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Hongfei Chen

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Open access Aug 2026

A Novel FAM83H Truncation Mutation Disrupts Enamel Mineralization in Autosomal Dominant Hypocalcified Amelogenesis Imperfecta

These findings are consistent with the “presecretory pathogenesis” model for ADHCAI, wherein nuclear‐mislocalized truncated FAM83H may disrupt enamel mineralization partly through transcriptional suppression of matrix components.

Yue Wang, Hongfei Chen, Jiyong Lai et al. · 0 citations

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