Author

Hongfei Tian

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Open access Aug 2026

Loss of LATS1 promotes immune evasion in colon cancer via YAP/TEAD-driven lactate metabolism reprogramming

A novel LATS1–LDHA–lactate axis that drives immune evasion in colon cancer through metabolic remodeling is identified, highlighting LATS1 as a potential therapeutic target for enhancing anti-tumor immunity.

Zhe Zhang, Hankun Liu, Yuxuan Li et al. · Scientific Reports · 0 citations