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Author

Hongkai Dai

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Jul 2026

Prophylactic polydatin protects against sepsis-induced muscle atrophy by suppressing endoplasmic reticulum stress via SIRT3 upregulation in a mouse CLP model.

Results demonstrated that PD intervention markedly reduced protein degradation mediated by the ubiquitin-proteasome system and attenuated sepsis-induced muscle atrophy, highlighting its potential as a protective strategy against this clinical condition.

Yingfang Zheng, Hongkai Dai, Ting-ting Xu et al. · 0 citations

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