Author

Honglei Shen

2 papers indexed here

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Review Open access Oct 2026

Neutrophil dysregulation in sepsis-induced acute lung injury: mechanistic framework and therapeutic targeting by natural products

Sepsis-induced acute lung injury (SALI) is an important complication of sepsis associated with substantial morbidity and mortality, yet effective targeted therapies remain limited. Neutrophils are central effectors of innate immunity and play indispensable roles in early antimicrobial defense. However, during sepsis, p...

Hui-Ling Luo, Jin-Yuan Lin, Hong-Lei Shen et al. · Frontiers in Pharmacology · 0 citations

Review Open access Aug 2026

Perioperative stress–inflammation–immunosuppression axis and tumor progression: mechanistic integration and anesthetic management strategies

Perioperative stress is an unavoidable part of surgery and may be particularly relevant in patients with cancer. Surgical trauma activates two major stress pathways, the hypothalamic–pituitary–adrenal (HPA) axis and the sympathetic nervous system (SNS), leading to surges in stress hormones, inflammatory mediators, and...

Liu Ye, Honglei Shen, Jinyuan Lin et al. · Holistic Integrative Oncolog... · 0 citations