Engineering the Enzyme-Support Interface: Arginine-Directed Anchoring of Peroxygenase on a β-Ketoester Covalent Organic Framework.
Controlling the conformation and orientation of enzymes at solid interfaces is a central challenge in the design of functional biohybrid materials, and the outcome depends sensitively on the chemistry and geometry of the enzyme-support interface. Here, a β-ketoester-functionalized keto-enamine covalent organic framewor...