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Hongpu He

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Open access Aug 2026

A multifunctional DECM/PLMA hydrogel incorporated with engineered PRP-derived exosomes enabling PHD2 silencing for skin wound repair

In both normal and diabetic murine full-thickness skin defect models, DEPL@E-SI significantly accelerated wound closure by promoting angiogenesis, inflammation resolution, and extracellular matrix remodeling, establishing DEPL@E-SI as a promising therapeutic platform with translational potential for skin tissue engineering and clinical wound management.

Xiangyu Du, Danmei Li, Hongpu He et al. · Bioactive Materials · 0 citations