Author

Hou-Juan Zhu

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Sep 2026

Hypertemperature-Detonated Biomimetic Semiconductor Stromal Bombs for Enhanced Immunotherapy in Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) is characterized by "copper avidity", which easily leads to the dysregulation of copper ion homeostasis. It is possible to develop targeted nanodrugs that selectively kill cancer cells via cuproptosis. However, the dense stroma of PDAC acts as an airtight wall, which not only lim...

Cheng-Ke Xie, Hou-Juan Zhu, Jian-Fan Wen et al. · Advances in Materials · 0 citations

Open access Aug 2026

Biodegradable Biomimetic Nanoplatform Orchestrating an Oxygen-Lactate Cascade to Enhance Photothermal Immunotherapy.

This work demonstrates a synergistic metabolic-photothermal immunotherapy strategy for efficient and long-lasting cancer treatment and achieves strong tumor accumulation, effective photothermal ablation, and combined with lactate depletion, complete tumor eradication without systemic toxicity.

Shuo Gao, Yu Chen, Yan-Xi He et al. · Advanced Healthcare Material... · 0 citations