Bladder cancer (BC), as the most common form of urothelial carcinoma, represents a substantial global health burden owing to its high rates of late diagnosis and disease recurrence. Current standard diagnostics, such as cystoscopy and tissue biopsy, are invasive, costly, and limited in capturing tumor heterogeneity or...
Can Chen, Yu-Ze Yang, Zhou-Hui Chen et al.· Journal of Translational Med...· 0 citations
Abstract Background Identifying robust predictive biomarkers for immune checkpoint blockade (ICB) remains a challenge. While alternative splicing (AS) shapes tumor immunity, the lack of large-scale, consensus-based datasets constrains the characterization of ICB-specific splicing landscapes. Methods We developed TCASIA...
Yi-Hao Zhang, Yun-Zhi Guo, Hai-Tao Wang et al.· Journal for ImmunoTherapy of...· 0 citations
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