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Author

Huajun Li

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Open access Sep 2026

An N-acetyltransferase influences AreA nuclear localization and nitrogen utilization in the basidiomycete Ganoderma lucidum.

Nitrogen metabolism is fundamental to fungal growth, development, and the biosynthesis of bioactive metabolites. The GATA transcription factor AreA plays a pivotal regulatory role in nitrogen metabolite repression. While the molecular mechanisms by which AreA responds to nitrogen sources have been relatively well eluci...

Hua-Jun Li, Jin-Jin Qiao, Shang-Shang Zhang et al. · 0 citations
Open access Jul 2026

Heat stress-induced degradation of glutamine synthetase rebalances central carbon-nitrogen metabolism and promotes thermotolerance in Ganoderma lucidum

G glutamine synthetase (GS) is degraded by the ubiquitin-proteasome system and that this degradation acts as a metabolic switch to enhance thermotolerance in Ganoderma lucidum, highlighting a direct and rapid link between metabolic flux and thermotolerance.

Jinjin Qiao, Huajun Li, Yuzhen Yang et al. · 0 citations

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