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Open access Oct 2026

GSTP1 as a senescence-associated diagnostic candidate in prostate cancer: integrative bioinformatics and functional validation

Prostate cancer (PCa) is a common malignancy of the male genitourinary system with high metastatic potential and poor clinical outcomes, for which effective biomarkers and therapeutic targets remain limited. This study employed a multi-omics approach, integrating transcriptome profiles, age-related gene scre...

Hou-He Li, Shuo Lu, Hua Wang et al. · 0 citations
Open access Oct 2026

Integrative Multi-Omics Reveals TSPAN13 as a Candidate Epithelial–Mesenchymal Transition-Associated Regulator in Prostate Cancer

Background: Prostate cancer (PCa) is a malignancy with high metastatic potential and poor prognosis, underscoring the urgent need for effective biomarkers and therapeutic targets to improve clinical management. Methods: An integrative multi-omics analysis combined with machine learning algorithms was performed to ident...

Shuo Lu, Hou-He Li, Zi-Xiao Zhang et al. · 0 citations

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