Predicted mechanisms of Huaier in hepatocellular carcinoma therapy via IL-2/PI3K-Akt immunomodulation: An integrated multi-method study.
ETHNOPHARMACOLOGICAL RELEVANCE Huaier (Trametes robiniophila Murr.; syn. Vanderbylia robiniophila (Murrill) B.K. Cui & Y.C. Dai), a medicinal fungus, has been traditionally used in China for adjuvant treatment of hepatocellular carcinoma (HCC). While promising, comprehensive high-quality evidence for its efficacy and a...