Hua-Wen Zhong

Unify learns cellular evolution with universal multimodal embeddings

Integrating single-cell RNA-sequencing (scRNA-seq) data across species is hindered by evolutionary divergence, technical batch effects, and the reliance on one-to-one orthologs. Here, we present Unify, a transfer learning methodology that learns universal cell embeddings by defining functionally coherent, multi-modal m...