Aug 2026
Mitochondria-Targeted Pyroptosis Orchestrated by Photodynamic Microneedle Patches Potentiates Melanoma Immunoradiotherapy.
The lethality of melanoma stems from its high metastatic propensity, intrinsic apoptosis resistance, and a profoundly immunosuppressive microenvironment, which collectively undermine conventional radiotherapy and immunotherapy. Here, we develop a spatiotemporally precise therapeutic strategy using mitochondria-targeted...
Ziyao Lu, Xinyu He, Yuwei Wang et al.
· Advances in Materials · 1 citation