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Review Sep 2026

The Gut-Liver Axis in Metabolic Dysfunction-Associated Steatotic Liver Disease and Associated Hepatocellular Carcinoma: Pathogenesis and Therapeutic Interventions.

Metabolic dysfunction-associated steatotic liver disease (MASLD) comprises a spectrum of liver diseases from simple steatosis to metabolic dysfunction-associated steatohepatitis and its associated fibrosis, cirrhosis, and MASLD-associated hepatocellular carcinoma (MASLD-HCC). MASLD affects over one-third of the global...

Huai Qian, Xiao-Lei Li, Hua Wang et al. · 0 citations
Aug 2026

GDF15 ameliorates inflammatory arthritis-associated bone destruction and pain through inhibition of osteoclastogenesis and modulation of osteoclast-derived Netrin-1/CGRP+ nerve remodeling.

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation, progressive bone erosion, and persistent pain, with limited therapeutic options for comprehensive disease control. Growth differentiation factor 15 (GDF15), a stress-responsive cytokine, has been implicated in i...

Li-Juan Mao, Haoran Huang, Zhen Shao et al. · 0 citations

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