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Oct 2026

Abstract C119: Characterizing FOXC1 dysregulation in triple-negative breast cancer to advance precision therapies and reduce cancer health disparities

Breast cancer is the most common cancer in women and the second leading cause of cancer death in the United States. Breast cancer has multiple subtypes defined by the expression of the estrogen receptor (ESR1), progesterone receptor (PGR), and human epidermal growth factor receptor 2 (HER2). Among breast cancer subty...

Chung S. Lee, Huan Cao, Vannah Algador et al. · 0 citations
Open access Jul 2026

Decoding 3D chromatin architecture reveals distinct enhancer classes underlying hierarchical gene regulation in prostate cancer

The findings suggest that enhancers function in a coordinated manner, forming multi-connected cancer-specific chromatin interaction hubs, with distinct enhancer classes contributing differently to gene regulation.

Huan Cao, Zexun Wu, Baixi Ji et al. · 0 citations

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