Open access
Sep 2026
Repurposing SKQ1 as a meropenem potentiator against NDM-1-producing Escherichia coli
ABSTRACT The widespread dissemination of New Delhi metallo-β-lactamase-1 (NDM-1) has severely compromised the clinical efficacy of carbapenem antibiotics, highlighting the need for strategies to restore meropenem activity. SKQ1 was identified through surface plasmon resonance (SPR)-based screening. Broth microdilution...
Xiao-Dan Li, Zi-Yi Zhang, Zhao-Ran Zhang et al.
· Virulence · 0 citations