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Huan-Huan Tang

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Open access Aug 2026

Multimodal Analysis Reveals Aberrant Expression of SUMO2 and Its Significant Association With Key Mechanisms of Metabolic Pathways in Hepatocellular Carcinoma.

BACKGROUND Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. However, the role of small ubiquitin-like modifier 2 (SUMO2), a core member of the small ubiquitin-like modifier (SUMO) family, regarding its expression patterns and metabolism-related functions in HCC remains inade...

Yu-Long Deng, Bei-Bei Huang, Yu-Xing Tang et al. · 0 citations
Open access Aug 2026

Multi-omics analysis reveals ANAPC1 overexpression and a potential TEAD4-associated regulatory relationship in cholangiocarcinoma

Cholangiocarcinoma (CHOL) is a highly heterogeneous and aggressive malignancy that is frequently diagnosed at an advanced stage because of the lack of early biomarkers, resulting in a poor prognosis. Although ANAPC1 overexpression has been reported in other cancers, its role and regulatory mechanisms in CHOL rema...

Ke-Jun Wu, Lei Wang, Yan-Ting Zhan et al. · 0 citations

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