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Author

Huantian Cui

3 papers indexed here

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Sep 2026

Sinapine thiocyanate (ST) ameliorates endothelial cell dysfunction by targeting chloride intracellular channel 4 (CLIC4) to treat hypoxia-induced pulmonary hypertension.

BACKGROUND AND PURPOSE Sinapine thiocyanate (ST) has effects in treating respiratory diseases. Its action in hypoxic pulmonary hypertension (HPH) remains poorly understood. We evaluated the potential of ST on HPH and its molecular mechanism. EXPERIMENTAL APPROACH ST was evaluated on a rat model HPH. Single-cell RNA s...

X. Gong, Yu-Ming Wang, Shi-Wei Kang et al. · 0 citations
Open access Jan 2026

Diosmetin Restores Endoplasmic Reticulum Homeostasis to Ameliorate Podocyte Injury in Diabetic Kidney Disease by Targeting DNAJC3

This study clarifies the molecular basis of DIO‐mediated protection in DKD, particularly in podocytes, by identifying DNAJC3 as a potential target that DIO inhibits ERS, restores ER homeostasis, and alleviates podocyte injury.

Tian-Yu Zhang, Na Zhao, Tong-Jin Liu et al. · 0 citations
Aug 2026

Shaoyao decoction inhibits neutrophil migration and restores epithelial integrity in ulcerative colitis model mice: insights from single-cell sequencing.

Functional pathway analysis indicated that neutrophil migration, epithelial tight junction regulation, and apoptosis were key processes modulated by Shaoyao Decoction, which exerts potent therapeutic effects against UC.

Huan-Tian Cui, Huan Pei, Fei-Tian Min et al. · 1 citation

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