Author

Huang-Tao Ruan

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Open access Sep 2026

Associations of long-term PM2.5 exposure and genetic susceptibility with prevalent metabolic syndrome and subsequent cardiovascular disease risk: A UK Biobank cohort study.

Findings indicate that long-term PM2.5 exposure is associated with prevalent MetS and subsequent CVD risk among individuals with MetS, particularly among genetically susceptible individuals, with DNA methylation potentially serving as an epigenetic link in these associations.

Zi-Yue Li, Hao-Zhang Huang, Jin-Ming Chen et al. · Ecotoxicology and Environmen... · 0 citations

Open access Aug 2026

Life's Essential 8 Score and Cardiovascular-Kidney Outcomes in ASCVD: A UK Biobank Prospective Cohort Study.

Higher LE8 scores were associated with lower risks of MACE and CKD in ASCVD patients, and high LE8 achievement may attenuate risks toward non-ASCVD levels.

Xiao-Zhao Lu, Zi-Yao Yuan, Guo-Shuai Yuan et al. · JACC: Advances · 0 citations

Open access Aug 2026

Integrated proteomic, transcriptomic, and epigenomic profiling identifies SRA1 as a novel therapeutic target for postpartum depression

This study reveals that SRA1 is a novel therapeutic target for PPD, which enhances the understanding of its molecular aetiology and the development of therapeutic strategies.

Ming Chen, Qinlin Wei, Hao-Wen Li et al. · npj Mental Health Research · 0 citations

Jul 2026

Sex-specific effects of depression on the incidence and risk factors for coronary heart disease: insights from multi-omics approaches.

Findings highlight significant sex differences in the effect of depression on CHD risk, which could inform sex-specific preventive strategies for reducing the cardiovascular burden in individuals with depression.

Haozhang Huang, Ming Chen, Xiao-Zhao Lu et al. · European Journal of Preventi... · 0 citations