Huanqing Yang

Mineralocorticoid receptor signaling in GABAergic neurons regulates stress-induced cognitive flexibility

These findings suggest that MRs in GABAergic neurons normally function as critical constraints on excitatory synaptic plasticity during high-stress states, underscoring that adaptive stress responses rely on a finely tuned, cell-type-specific balance of corticosteroid signaling within limbic microcircuits.