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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Hui Deng

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Open access Oct 2026

METTL3 Increases Temozolomide Resistance in MGMT‐Negative Glioblastoma by Enhancing CBX5 mRNA Stability in an m6A‐IGF2BP2‐Dependent Manner

ABSTRACT Aims We examined whether chromobox protein 5 (CBX5) contributes to temozolomide (TMZ) resistance in O6‐methylguanine‐DNA methyltransferase (MGMT)‐negative glioblastoma (GBM) and whether it is regulated by methyltransferase‐like 3 (METTL3)‐dependent N6‐methyladenosine (m6A) and insulin‐like growth factor 2 mRNA...

Hui Deng, Ruo-Yu Chen, Dao-Hong Qu et al. · 0 citations

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