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Open access Sep 2026

Targeting TREM2+ and TIMD4+ Macrophages Reprograms the Tumor Microenvironment and Enhances PD-1 Blockade Efficacy in Intrahepatic Cholangiocarcinoma

Background: Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer. Macrophages are crucial components of the tumor microenvironment (TME). Triggering receptor expressed on myeloid cells 2-positive (TREM2+) macrophages have recently emerged as potent pro-tumor progress players in several c...

Yao Li, Hong-Wen Liu, Lei Xu et al. · 0 citations
Sep 2026

SlideChat is a multimodal generative artificial intelligence assistant for whole-slide computational pathology across cancer types

SlideChat, a multimodal generative artificial intelligence assistant for whole-slide computational pathology across cancer types, outperformed leading baselines in closed-ended accuracy and report-generation Metric for Evaluation of Translation with Explicit Ordering score and received the highest expert ratings across...

Ying Chen, Chenglong Ma, Qiong-Qiong Li et al. · 2 citations

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