Elucidating the potential anti-liver cancer mechanisms of the medicinal food Rosa roxburghii Tratt. by integrating HPLC-Q Exactive MS/MS, network pharmacology, and in vitro validation.
This study integrated HPLC-Q Exactive Plus MS/MS analysis, network pharmacology, molecular docking, and in vitro assays to investigate the anti-liver cancer mechanisms of flavonoid components from Rosa roxburghii Tratt. (RRT) ethanol extract. A total of 52 flavonoids were identified, including 15 active compounds assoc...