Abstract Objectives To analyse temporal trends, clinical outcomes and healthcare costs of Alzheimer’s disease (AD)-related hospitalisations in Southwest China over 14 years and identify modifiable risk factors for adverse outcomes. Design Retrospective time-series analysis of electronic health records. Setting A tertia...
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by motor neuron degeneration. Although metabolic abnormalities have been implicated in ALS, the causal relationships between circulating metabolites and ALS remain unclear. This study aimed to investigate the potential causal...
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis typically presents with psychiatric symptoms, seizures, and cognitive dysfunction. Movement disorders, when present, usually coexist with these features. We report a rare case of anti-NMDAR encephalitis in a 30-year-old female who presented with isolated left...
Youjia Liu, Si-Hui Chen, Yan-Yun Wu et al.· Frontiers in Immunology· 0 citations
Amyotrophic lateral sclerosis (ALS), the most common type of motor neuron disease, primarily manifests as progressive weakness, atrophy, fasciculations, bulbar palsy, and pyramidal tract symptoms. Accumulating evidence indicates that the pathological spectrum of ALS extends beyond the pyramidal and neuromuscular motor...
Xin-Yao Gao, Ting-Ting Wang, Si-Hui Chen et al.· Frontiers in Genetics· 0 citations
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