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Open access Sep 2026

Development of an early warning model for sepsis-associated encephalopathy using LASSO-Boruta-Logistic regression.

OBJECTIVE This study aimed to develop an early warning model for sepsis-associated encephalopathy (SAE) to facilitate early clinical identification and intervention. METHODS Clinical data from 631 patients diagnosed with sepsis and admitted to Hebei General Hospital between September 2023 and June 2025 were retrospec...

Yu-Bo Wei, Hong-Ling Li, Hua-Yang Han et al. · 0 citations
Aug 2026

Isoquercitrin alleviates sepsis-induced myocardial injury via the EGFR/PI3K/AKT signaling pathway.

BACKGROUND Sepsis-induced myocardial injury is a life-threatening complication. Isoquercitrin (IQC), a natural flavonoid glycoside, exhibits anti-inflammatory and anti-apoptotic properties, yet its role in septic cardiomyopathy remains unclear. METHODS IQC targets were predicted via transcriptomics and molecular dock...

Hexin Zhai, Xingwei Yang, Yan Shao et al. · 0 citations

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