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Open access Oct 2026

A biomimetic dual-targeting nanoplatform enhancing pyroptosis and chemosensitization for precision therapy of diffuse large b-cell lymphoma

To elucidate the role of SHP-2 in regulating pyroptosis through the TXNIP‑NLRP3 inflammasome axis in diffuse large B‑cell lymphoma (DLBCL) and to evaluate the therapeutic efficacy and safety of a SHP099‑loaded B‑cell membrane–CD20 aptamer dual‑targeting biomimetic nanoplatform (SHP099@Bmem‑AptCD20). SHP-2...

Jing-Xuan Lian, Xiao-Hui Duan, Wen-Jie Chen et al. · 0 citations

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