Author

Hui-Hui Chen

3 papers indexed here

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Review Open access Sep 2026

From gut to lung: the microbiome-directed causal mechanisms and therapeutic horizons in asthma

The gut–lung axis represents a predominantly gut-to-lung communication network through which gut microbiota and their metabolites influence pulmonary immunity. In asthma, gut dysbiosis—characterized by reduced microbial diversity, depletion of short-chain fatty acid (SCFA)-producing taxa, and expansion of pro-inflammat...

Feng-Xian Ni, Chun-Feng Pan, Hui-Hui Chen et al. · Frontiers in Immunology · 0 citations

Review Open access Oct 2026

The cGAS-STING pathway in ovarian cancer: from genomic instability to immunotherapeutic vulnerability

Ovarian cancer remains the most lethal gynecologic malignancy, a status largely attributable to late-stage diagnosis and inevitable chemoresistance. The cGAS-STING pathway, a cornerstone of innate immune surveillance, has emerged as a critical nexus linking genomic instability to antitumor immunity—a connection of pa...

Hui-Hui Chen, Feng-Xian Ni, Dong-Hui Huang et al. · Frontiers in Immunology · 0 citations

Review Open access Aug 2026

Epitranscriptomics, immunometabolism, and NETosis: unlocking novel mechanisms of traditional Chinese medicine in COPD

The bidirectional metabolism-m6A crosstalk as a theoretical framework requiring experimental validation, and single-cell m6A sequencing, spatial metabolomics, and CRISPR screening as tools to accelerate precision TCM for COPD are outlined.

Hui-Hui Chen, Feng-Xian Ni, Dong-Hui Huang et al. · Frontiers in Immunology · 0 citations