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Author

Hui-Jiuan Chen

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Sep 2026

Functionalized Spiky Microcarriers Orchestrate STING Activation and Durable Antitumor Immunity

The stimulator of interferon (IFN) genes (STING) pathway has garnered considerable attention due to its significant potential in anti-cancer effect. However, cyclic dinucleotides (CDNs), which are natural agonists or their derivatives for STING, are often hindered by their inherent properties of poor transmembrane pe...

Li-Ru Shang, Lin Peng, Zhang-Ping Huang et al. · 0 citations
Open access Aug 2026

An integrated nanopore–microfluidic platform for low-voltage electroporation of delivering self-amplifying RNA into dendritic cells

This reagent-minimal, modular NEP platform provided a high-efficiency, low-toxicity route for saRNA delivery into hard-to-transfect immune cells, offering a versatile engineering framework for DC-based cancer immunotherapy, RNA vaccine development, and broader cell gene-modification applications.

Bowen Zhang, Yi-Jing Cai, Caiguanxi Deng et al. · 0 citations

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