Hui-Lin Yang

Biomaterials for intervertebral disc regeneration: Niche reprogramming, precision therapeutics, and structural reconstruction

Intervertebral disc degeneration (IDD) arises from coupled redox imbalance, inflammation, cellular senescence, nutrient limitation, matrix loss, and mechanical failure. Biomaterials can localize therapy within the avascular disc while combining microenvironmental control with structural support. However, many studies s...