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Review Open access Sep 2026

From mitochondria to innate immunity: The mtDNA-driven cGAS/STING-NLRP3 cascade and its therapeutic implications in neurodegenerative diseases (Review)

A modular assessment framework was proposed across the ‘input-chronicity-amplification’ layers and the potential of mtDNA-cGAS/STING-NLRP3 axis-informed stratified diagnosis and treatment was discussed.

Hui Liu, Yao Zhang, Zi-Liang Zhuo et al. · 0 citations

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