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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Hui-Nan Ren

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Sep 2026

Synthesis of Chiral Benzylamines via Nickel-Catalyzed Enantioselective C–H Alkynylation

The enantioselective C–H functionalization of benzylamines using earth-abundant metal catalysts remains a formidable challenge due to conformational flexibility and long-range chiral induction. Herein, we describe a Ni(II)-catalyzed enantioselective C–H alkynylation of benzylamines using a removable picolinamide dire...

Tian-Yu Jiang, Hui-Nan Ren, Jia-Hao Chen et al. · 0 citations

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