Pancreatic development is a tightly orchestrated process driven by the concerted action of multiple signaling pathways. Fibroblast growth factors (FGFs) serve as pivotal cues across its stages: they engage FGF receptors (FGFRs) to activate downstream ERK/MAPK, PI3K-AKT, and PLCγ cascades, thereby governing pancreatic p...
Z. Dou, Ying-Ling Jiang, Xin Liu et al.· Cytokine & growth factor rev...· 0 citations
This review summarizes the multifaceted roles of AS in lung cancer biology, highlighting its contributions to tumor evolution, metastatic dissemination, and treatment resistance and its potential implications for biomarker discovery and precision therapeutic strategies targeting splicing dysregulation.
Lingrui Shang, Nannan Wang, Qianqian Liu et al.· International Journal of Mol...· 0 citations
This reporter line enables real-time tracking of FCGR3A expression during immune cell differentiation, serving as a useful tool for studying FCGR3A-EGFP knock-in human embryonic stem cell (hESC) line via CRISPR/Casn9n.
Qifei Dong, Shahang Luo, Jiaqi Sun et al.· Stem Cell Research· 0 citations
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