Hui-Song Yang

Innovative Approach to Pt(IV) Complexes: Addressing the Limitations of Traditional Chemotherapy Through Targeted Delivery and Multifunctional Design.

Platinum-based chemotherapy remains a cornerstone of cancer treatment. However, classical Pt(II) drugs, including cisplatin, carboplatin, and oxaliplatin, show significant limitations. They induce systemic toxicity, show poor tumor-targeting capability, and give rise to drug resistance. These issues result in treatment...