The brain’s immune code: decoding antigen presentation at the meningeal-glymphatic interface in neurological disorders
The classical view of central nervous system (CNS) immune privilege has evolved from isolation to regulated crosstalk. Perivascular cerebrospinal fluid-interstitial fluid transport and meningeal lymphatic vessels (mLVs) move brain-derived molecules toward immune-rich border tissues and cervical lymph nodes, where antig...