Author

Hui-Yu Liu

3 papers indexed here

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Open access Oct 2026

Sequence-specific and programmable catalytic degradation of extracellular microRNAs by membrane-anchored DNA nanomachines

Extracellular microRNAs (miRNAs) contribute to metastasis through communication between tumour cells and their microenvironment, yet their sustained, sequence-selective depletion remains challenging. Here we report Programmable RNA-Intercepting Molecular Eraser (PRIME), a membrane-anchored DNA nanomachine that organize...

Zi-Yan Zhou, Ling-Hao Zhang, Xiao-Wei Wang et al. · bioRxiv · 0 citations

Review Oct 2026

Hypoxia-Regulating Nanozymes for Biomedicine.

Hypoxic microenvironments arise when local oxygen supply fails to meet cellular demand and exert an influence on the progression of cancer, ischemic heart and brain injury, chronic inflammatory disorders, and other diseases. Conventional approaches, including oxygen delivery systems, small-molecule redox drugs, and nat...

Yu-Han Yang, Yun Sun, Xing Sun et al. · Advances in Materials · 0 citations

Open access Sep 2026

Nanozyme-Assisted Engineered Oncolytic Adenovirus for Improving Intratumoral Immune Deficiency and Enhancing Cancer Immunotherapy.

Oncolytic adenovirus (OA) exhibit tumor-selective tropism, inducing direct oncolysis while simultaneously potentiating host immune responses against malignancies. However, the poor delivery efficiency of the virus targeting tumors and its limited immune activation capacity severely delays the therapeutic effect. This s...

Yu-Qing Lv, Qing-Yuan Wu, Ao-Di Niu et al. · Advances in Materials · 0 citations