Conventional pharmaceutical manufacturing is optimized for standardized fixed-dose products and offers limited flexibility for patients requiring individualized dosing, patient-acceptable dosage forms, or multidrug therapy. Semi-solid extrusion (SSE) 3D printing can process gels, pastes, suspensions, and other viscoela...
Bai-Yi Zeng, Xiao-Lu Han, Jia Li et al.· International journal of pha...· 0 citations
A programmable DNA origami-based lateral flow assay (DO-LFA) that employs a triangular DNA origami nanostructure (TDON) as a tunable molecular scaffold offering a generalizable and scalable strategy for next-generation point-of-care diagnostics.
Bao-Hong He, Xi-Wei Wang, Xiao-Lu Han et al.· Biosensors & bioelectronics· 0 citations
This review provides an integrated overview of recent advances in mRNA-LNP vaccines, covering mRNA molecular engineering, LNP composition and delivery mechanisms, immune responses, clinical progress, and current developmental challenges.
Zhi-Neng Wu, Jinghu Lou, Yi Cheng et al.· Molecular Biomedicine· 0 citations
By orderly assembling nanobodies on DNA origami, this study creates a biomimetic nanoscale trap with triple functions-"capture, enrichment, and sequestration"-against BoNT/A, which provides a highly efficient neutralization paradigm for anti-BoNT/A therapy and highlights the transformative potential of DNA origami nano...
You-Qing Chu, Xi-Wei Wang, Yabing Hua et al.· ACS Applied Bio Materials· 0 citations
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