Anthracycline-induced cardiotoxicity remains a major limitation in cancer therapy, with substantial inter-individual variability in susceptibility, including documented sex differences. However, the molecular basis underlying these disparities remains incompletely understood. In this study, we employed large-scale data...
Sogol Sedighi, Li-Jun Chen, Yue-Fen Wang et al.· Journal of Molecular and Cel...· 0 citations
High-grade gliomas (HGGs) in children and adolescents and young adults (AYA) exhibit distinct biology across the neurodevelopmental spectrum. To dissect tumor-intrinsic molecular characteristics independent of developmental variation, we perform comprehensive proteogenomic analyses of tumors from 112 HGG patients aged...
N. Tignor, M. Koptyra, Shrabanti Chowdhury et al.· Cell Reports Medicine· 0 citations
Mass spectrometry (MS)-based multi-omics offers powerful tools to comprehensively characterize proteins, post-translational modifications, metabolites, and lipids. However, these measurements are typically performed using separate sample preparation workflows and modality-specific liquid chromatography mass spectrometr...
Yuefan Wang, X. Peng, Hongyi Liu et al.· Chemical Communications· 0 citations
A novel approach to identify pig xenoantigens, including peptide and glycopeptide epitopes, that react with human-preformed antibodies that could guide genetic engineering strategies and enhance recipient candidate screening for xenotransplantation, ultimately increasing the feasibility and success of xenogeneic organ...
Hongyi Liu, Trung Hoàng, Ying Hu et al.· Journal of Proteome Research· 1 citation
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