LncRNA 34962 drives pulmonary vascular remodeling in pulmonary hypertension due to left heart disease through the miR-3575/cMYC/TERT signaling axis.
BACKGROUND Pulmonary hypertension due to left heart disease (PH-LHD) is the most prevalent form of pulmonary hypertension, characterized by pulmonary vascular remodeling driven by abnormal proliferation and migration of pulmonary artery smooth muscle cells (PASMCs). Although long non-coding RNAs (lncRNAs) regulate card...