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Author

Hui Zheng

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Sep 2026

STC1 promotes monosodium urate crystal-induced gouty inflammation via the cAMP-PKA-NF-κB/NLRP3 pathway in mice.

Gouty arthritis (GA) is driven by NLRP3 inflammasome-dependent pyroptosis. Stanniocalcin-1 (STC1) is a secreted glycoprotein implicated in inflammatory regulation, but its role in GA is unclear. This study examined whether STC1 promotes MSU-induced NLRP3 activation and pyroptosis via cAMP-PKA signalling and interaction...

Yue He, Hui Zheng, Zhi Yue et al. · 0 citations

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