Review
Aug 2026
Targeting the Ubiquitin-Proteasome System: An Emerging Paradigm for Overcoming Resistance to Targeted Therapy in Non-Small Cell Lung Cancer.
The molecular mechanisms by which the UPS contributes to targeted therapy resistance in NSCLC are summarized, recent progress in emerging UPS-targeting strategies are evaluated, and the major barriers impeding their clinical translation are critically discussed.
Ruizhi Chen, Hui Zhu, Kailang Zhou et al.
· Experimental Cell Research · 0 citations