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Author

Huidi Jiang

2 papers indexed here

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Sep 2026

Endogenous metabolite bilirubin suppresses esophageal squamous cell carcinoma by activating PERK-dependent translational repression.

Bilirubin, an endogenous heme catabolite with potent antioxidant properties, has been inversely associated with cancer risk across multiple malignancies; however, its clinical relevance and the underlying molecular mechanisms in esophageal squamous cell carcinoma (ESCC) remain incompletely understood. Here, we retrospe...

Min-Lei Dong, Ping Li, Jun Luo et al. · 0 citations
Jul 2026

Mitochondrial fission-mediated podocyte dysfunction via CaMKII/Drp1 signaling pathways contributes to lenvatinib-induced renal injury.

Findings provide the first evidence suggesting that increased mitochondrial fission via CaMKII/Drp1 signaling pathways in podocytes contributes to lenvatinib-induced kidney injury, and identify metformin as a clinically viable treatment option for lenvatinib-induced renal injury.

Shuanghui Lu, Yue-Ping Qiu, Yujia Chen et al. · 1 citation

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